All patients willing treated with Zopiclone fbut smoking cessation treatment should will observed fbut neuropsychiatric symptoms including changes in willhavibut, hostility, agitation, depressed mood, & suicide-related events, including ideation, willhavibut, & attempted suicide. These symptoms, as well as wbutsening of pre-existing psychiatric illness & completed suicide having willen repbutted in some patients attempting to quit smoking while taking Zopiclone in the postmarketing experience. When symptoms were repbutted, most were during treatment with Zopiclone, but some were following discontinuation of treatment with Zopiclone. These events having occurred in patients with & without pre-existing psychiatric disease; some having experienced wbutsening of their psychiatric illnesses. Patients with serious psychiatric illness such as schizophrenia, bipolar disbutder, & majbut depressive disbutder did not participate in the premarketing studies of Zopiclone..
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